关于学院

高建

职务: 副教授
邮箱: gaojianayfy@163.com
专业: 药理学

Education/Working Experience

1994/09--1998/07  Anhui Chinese Medicine University Bachelor

2001/09--2004/07  Anhui Medical University  Master

2006/09--2009/07  Anhui Medical University  PhD

2009/11--2015/10  The First Hospital of Anhui Medical University   AssociateChief Pharmacist

2015/11--Present The Second Hospital of Dalian Medical University   ChiefPharmacist;Director of Division of Research and Development Department ; Associate Director of pharmaceutical department

Participation in the Academic Community

SeniorMember of ChinesePharmaceuticalAssociation

Standing Committee Member of Tonicpharmacology ofChinesePharmacologicalSociety

Standing Committee Member of  PharmaceuticPreparationofChina Association of Chinese Medicine

Member of ChineseCrudeDrugProcessing ofChina Association of Chinese Medicine

Publication

1. Total Glucosides of Danggui Buxue Tang Attenuate BLM-Induced Pulmonary Fibrosis via Regulating Oxidative Stress by Inhibiting NOX4. Oxidative Medicine and Cellular Longevity.(IF:4.492)

2. High-Mobility Group Box 1 Mediates Epithelial-to-Mesenchymal Transition in Pulmonary Fibrosis Involving Transforming Growth Factor-β1/Smad2/3 Signaling. Journal of pharmacology and experimental therapeutics.(IF:3.972)

3.  Inositol-requiring protein 1-X-box-binding protein 1 pathway promotes epithelial-mesenchymal transition via mediating snail expression in pulmonary fibrosis. International journal of biochemistry & cell biology.(IF:3.905)

4. Total extract of Yupingfeng attenuates bleomycin-induced pulmonary fibrosis in rats. Phytomedicine.(IF:2.937)

5. Total  glycosides of Yupingfeng protects against bleomycin-induced pulmonary fibrosis in rats associated withreduced high mobility group box1 activation and epithelial-mesenchymal transition. Inflamm Res.(IF:2.347)

6. Total Polysaccharide of Yupingfeng Protects against Bleomycin-Induced Pulmonary Fibrosis via Inhibiting TGF-ß1-Mediated Type I Collagen Abnormal Deposition in Rats. Journal of Pharmacy and Pharmacology.(IF:2.363)

7. Functions of galectin-3 and its role in fibrotic diseases. Journal of pharmacology and experimental therapeutics.(IF:3.972)

8. Emerging role of HMGB1 in fibrotic diseases. Journal of cellular and molecular medicine.(IF:4.938)

9. Total glucosides of Danggui– Buxue–Tang attenuates bleomycin-induced pulmonary fibrosis via inhibition of extracellular matrix remodeling. Journal of Pharmacy and Pharmacology.(IF:2.363)

10. Total glucosides of Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-beta1/Smad pathway and altering the MMP2/TIMP1 ratio. Journal of Ethnopharmacology.(IF:3.055)

Research Projects/Grants

1. Natural Science Foundation of China, 81473267, P62 regulates Keap1-Nrf2-ARE signaling pathway during PF, 2015/01-2018/12.

2. Natural Science Foundation of China, 81274172, Nrf2 regulates TGFβ-Smad signaling pathway in oxidative stress-induced PF and the mechanism of Total glucosides of Danggui–Buxue–Tang, 2013/01-2016/12.

Admission Plan/Requirements

Admission Plan:1-2 foreign postgraduate

Requirements: Decent English level;Healthy ;Honesty; Hard-Working