Education/Working Experience

2015-present  Professor, Dalian Medical University

          Research Focus: Role of glia-mediated neuroinflammation in neurodegeneration

2014-2015    Research Fellow, National Institute of Environmental Health Sciences

            Research Focus: Role of glia-mediated neuroinflammation in

pre-motor/non-motor symptoms of Parkinson’s disease

2009-2014    Visiting Fellow, National Institute of Environmental Health Sciences

            Research Focus: Role of microglia in inflammation-mediated

neurodegeneration in Parkinson’s disease: models,

mechanisms, and therapeutic interventions

2006-2009     Doctor of Medicine, School of Public Health, Shandong University

2003-2006     Master of Medicine, School of Public Health, Shandong University 1998-2003     Bachelor of Medicine, School of Public Health, Shandong University

Participation in the Academic Community

EDITORIAL BOARD MEMBER

2013-present    Journal of Toxins

2013-present    Journal of Bioequivalence & Bioavailability

2013-present    International Journal of Neuroscience and Behavioral Science

REVIEWER FOR JOURNALS

PloS One

Brain Research

NeuroToxicology

Toxicology in vitro

Neurotoxicology and Teratology

International journal of biological sciences

Publication

1. Wang Q*, Qian L, Chen SH, Chu CH, Wilson B, Esteban O, Ali S, Robinson B, Rao D, Hong JS*. Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models. Brain. 2015, 1247-1262.

2. Wang Q*, Oyarzabal E, Wilson B, Qian L, Hong JS*. Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice. Clinical Science. 2015, 757-767.

3. Jiang L, Chen S, Chu C, Wang S, Esteban O, Wilson B, Sanders V, Xie K*, Wang Q*, Hong J*. A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis. Glia. 2015, 1057-1072.

4. Chen SH, Oyarzabal EA, Sung YF, Chu CH, Wang Q, Chen SL, Lu RB, Hong JS. Microglial regulation of immunological and neuroprotective functions of astroglia. Glia. 2015, 118-31

5. Wang Q*, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS*. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. Journal of Neuroscience. 2014, 12490-503.

6. Wang Q, Chu CH, Oyarzabal E, Jiang L, Chen SH, Wilson B, Qian L, Hong JS. Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases. Glia. 2014, 2034-43.

7. Chu CH, Chen SH, Wang Q, Langenbach R, Li H, Zeldin D, Chen SL, Wang S, Gao H, Lu RB, Hong JS. PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition. Molecular Neurobiology. 2015, 587-600

8. Wang Q^#, Shin EJ^#, Nguyen XK, Li Q, Bach JH, Bing G, Kim WK, Kim HC, Hong JS. Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice. Journal of Neuroinflammation. 2012, 9:124.

9. Wang Q, Zhou H, Gao H, Chen SH, Chu CH, Wilson B, Hong JS. Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. Journal of Neuroinflammation. 2012, 9:32.

10. Chen SH, Wu HM, Ossola B, Schendzielorz N, Wilson BC, Chu CH, Chen SL, Wang Q, Zhang D, Qian L, Li X, Hong JS, Lu RB. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage. British Journal of Pharmacology. 2012, 165, 494-505.

11. Wang Q, Song F, Zhang C, Zhao X, Zhu Z, Yu S, Xie K. Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation. Biochemical Pharmacology. 2011, 793-9.

12. Feng J^#, Wang Q^#, Chiang A, Chen BY. The effects of sleep hypoxia on coagulant factors and hepatic inflammation in emphysematous rats. PLoS One. 2010, 5: e13201.

Research Projects/Grants

2015-2020 Principle Investigator: Grant of “QIZHEN Project”

2012-2015  Secondary Principle Investigator: National Natural Science Foundation

of China (No. 81172708)

2010-2012  Principle Investigator: National Natural Science Foundation of China

(No. 30901212).

Admission Plan/Requirements

One student each year.

The successful candidate will have:

1. A relevant bachelor or master degree;

2. An outstanding record of undergraduate or Master’s degree work;

3. Some background in or willingness to familiarize himself/herself with issues related to role of glia-mediated neuroinflammation in environmental toxins-induced neurodegeneration;

4. Strong oral and written communication skills in English and the ability to publish the results of research in scientific peer-reviewed journals;

5. Capacity to collaborate across the academic disciplines;

6. Ability to work both independently and as part of the team with good organizational and social skills.