Education/Working Experience

Education

June 2000  Ph.D. Dalian Medical University, Dalian, China.

Major: Biochemistry and Molecular Biology

May 1994  M.S. North Dakota State University, Fargo, USA

Major: Molecular Biology

July 1987   M.S. Beijing Normal University, Beijing, China.

Major: Genetics

July 1984   B.S. Henan Normal University, Xinxiang, China.

Major: Biology

Working Experience

June 2000 - present  Professor, Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian, China

June 2000 - Sept. 2001  Post-doctoral Fellow, Department of Microbiology, Colorado State University, Fort Collins, USA

May 1996 - June 2000  Associated Professor, Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian, China

July 1994 - April 1996  Research Associate, Department of Microbiology, Colorado State University, Fort Collins, USA

May 1989 - Dec. 1990  Research Assistant, Department of Food and Nutrition, North Dakota  State University, Fargo, USA

July 1987 - May 1989  Lecturer, Department of Cell Biology and Genetics, Henan Medical University, Zhengzhou, China

Participation in the Academic Community

Member of Chinese Society of Biochemistry and Molecular biology

Member of Chinese Society of Bioengineering

Member of Chinese Society of Microbiology

Publication

Shanshan Sha, Xiaoxia Shi, Liming Xu, Jiabin Wen, Yi Xin and Yufang Ma. Viability, morphology and proteome of M. smegmatis MSMEG_0319 knockout strain. Proteomics (2016),  doi: 10.1002/pmic.201500054.

Xiaoxia Shi, Shanshan Sha, Likun Liu, Xin Li, Yufang Ma. A microtiter plate assay for high-throughput screening of Mycobacterium tuberculosis dTDP-D-glucose-4, 6-dehydratase inhibitors. Analytic Biochemistry (2016), 498: 53-58.

Jianjun Liu, Qiulong Yan, Fuwen Luo, Dong Shang, Dachang Wu, Haiquan Zhang, Xueqi Shang, Xiaoli Kang, Meyiah Abdo, Beibei Liu, Yufang Ma and Yi Xin. Acute cholecystitis associated with infection of Enterobacteriaceae from gut microbiota. Clinical Microbiology and Infection (2015), 21(9):851.e1-9.

Shufeng Yang, Fei Zhang, Jian Kang, Wenli Zhang, Guoying Deng, Yi Xin, Yufang Ma. Mycobacterium tuberculosis Rv1096 protein: gene cloning, protein expression,and peptidoglycan deacetylase activity. BMC Microbiology (2014), 14: 174.

Xiao-Feng Yao, Jun Cao, Li-Ming Xu, Xian-Ce Sun, Jian Kang, Guang Yang, Li-Ping Jiang, Cheng-Yan Geng, Chuan-Zhou Gao, Lai-Fu Zhong, Yu-Fang Ma. Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells. Food and Chemical Toxicology (2014), 67: 96-104.

Liming Xu, Dongting Wu, Liang Liu, Qi Zheng, Yu Song, Li Ye, Shanshan Sha, Jian Kang, Yi Xin, Yufang Ma. Characterization of mycobacterial UDP-N-acetylglucosamine enolpyruvyle transferase (MurA). Research in Microbiology (2014), 165: 91-101.

Jian Kang, Liming Xu, Shufeng Yang, Wendan Yu, Shuo Liu, Yi Xin and Yufang Ma. Effect of phosphoglucosamine mutase on biofilm formation and antimicrobial susceptibilities in M. smegmatis glmM gene knockdown strain.  PLoS One (2013), 8(4): e61589.

Yan Zhou, Wendan Yu, Qi Zheng, Yi Xin and Yufang Ma. Identification of amino acids involved in catalytic process of M. tuberculosis GlmU acetyltransferase. Glycoconjugate Journal (2012), 29: 297-303.

Shuang Li, Jian Kang, Wendan Yu, Yan Zhou, Wenli Zhang, Yi Xin, Yufang Ma. Identification of M. tuberculosis Rv3441c and M. smegmatis MSMEG_1556 and essentiality of M. smegmatis MSMEG_1556. PLoS One (2012), 7(8): e42769.

Guang Yang, Shaopeng Wang, Laifu Zhong, Xu Dong, Wenli Zhang, Liping Jiang, Chengyan Geng, Xiance Sun, Xiaofang Liu, Min Chen and Yufang Ma. 6-Gingerol induces apoptosis through lysosomal-mitochondrial axis in human hepatoma G2 cells. Phytotherapy Research (2012), 26: 1667-1673.

Shanshan Sha, Yan Zhou, Yi Xin, Yufang Ma. Development of a colorimetric assay and kinetic analysis for Mycobacterium tuberculosis D-glucose-1-phosphate thymidylyltransferase. Journal of Biomolecular Screening (2012), 17(2): 252-257.

Yan Zhou, Yi Xin, Shanshan Sha, and Yufang Ma. Kinetic properties of Mycobacterium tuberculosis bifunctional GlmU.  Archives of Microbiology (2011), 193: 751-757.

Guang Yang, Laifu Zhong, Liping Jiang, Chengyan Geng, Jun Cao, Xiance Sun, Xiaofang Liu, Min Chen, Yufang Ma.  6-Gingerol prevents patulin-induced genotoxicity in HepG2 cells. Phytotherapy Research (2011), 25: 1480-1485.

Research Projects/Grants

Studies on the action mechanisms of inhibitors for M. tuberculosis GlmU acetyltransferase and evaluation of their inhibitory effects on M. tuberculosis. National Natural Science Foundation of China (81573469), 2016.01 - 2019.12, 540000 RMB.

The structures and functions of surface polysaccharides of pathogenic bacteria. National Basic Research Program of China (2012CB518803), 2012.01 - 2016.12, 460000 RMB.

The talent support program of Dalian Medical University. 2013 - 2016. 350000 RMB.

Admission Plan/Requirements

One Ph.D. student with background in Biology/Medicine