Education/Working Experience

EDUCATION

1. 09/1987 to 07/1992: Bachelor's degree of clinical medicine, Harbin Medical University, China

2. 09/1992 to 07/1995: M.D., Dalian Medical University, China


3. 09/2002 to 07/2005: Ph.D., Academy of Medical Sciences, Peking Union Medical College, China

WORKING EXPERIENCE

1. 07/1995 to 10/1997: Resident Doctor, DMU


2. 11/1997 to 10/2002: Attending Doctor, DMU

3. 11/2002 to 10/2007: Associate Professor, DMU

4. 11/2007 to present: Professor, DMU

Abroad Study

06/2013 to 09/2013: Visiting Scholar,Department of neurosurgery, Johns Hopkins Hospital and Massachusetts General Hospital, USA

Participation in the Academic Community

1. Member of China Pituitary Adenoma Specialist Council


2. Committee Member of Chinese Medical Doctor Association

3. Committee Member of Chinese Medical Association


4. Chairman of Liaoning Society of Neurologic Tumor LSCB

Publication

1. Guan J, Zhang B, Zhang J, Ding W, Xiao Z, Zhu Z, Han Q, Wu C, Suna Y, Tong W, Dai J and Wang R, Nerve Regeneration and Functional Recovery by Collagen-Binding Brain-Derived Neurotrophic Factor in an Intracerebral Hemorrhage Model, Tissue Eng Part A. 2015 Jan;21(1- 2):62-74

2. Wang W,Zhang B. Statins for the Prevention of Stroke: A Meta-Analysis of Randomized Controlled Trials*. Plos one, 2014, 9(3): e92388.

3. Zhang H, Liu H, Xu F, Zhang B. The Utilization Risk of Rivaroxaban in the Anti-Glioma Therapy Regimen. Latin American Journal of Pharmacy,2015,34(3):616-618


4. Lou J, Zhang H, Wang D, Yuan Z, Yu Z, Zhang B. Bioinformatics-Based Prediction of Drug Utilization Risk of Anti-Brain Tumor Drug Linifanib. Latin American Journal of Pharmacy,2015,34(7):1438-40


5. Yu Z, Li T, Wang C, Deng S, Zhang B^*, Huo X, Zhang B, Wang X, Zhong Y, Ma X^*. Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells. Oncotarget. 2016. doi: 10.18632/oncotarget.7398

6. Lv D^*, Wang X^*, Dong J, Zhuang Y, Huang S, Ma B, Chen P, Li X, Zhang B, Li Z, Jin B^*. Systematic characterization of lncRNAs' cell-to-cell expression heterogeneity in glioblastoma cells. Oncotarget. 2016. doi: 10.18632/oncotarget.7580.

7. DaiC, ZhangB ,LiuX, MaS, YangY, YaoY, FengM, BaoX, LiG, WangJ,GuoK,Ma W, Xing B, Lian W, Xiao J, Cai F, Zhang H, Wang R. Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice. Endocrinology , 2013; 154(3):1247-1259

8. Liu X, Ma S, Dai C, Cai F, Yao Y, Yang Y, Feng M, Deng K, Li G, Ma W, Xing B, Lian W, Xiang G, Zhang B, Wang R. Antiproliferative, Antiinvasive, and Proapoptotic Activity of Folate Receptor Į-Targeted Liposomal Doxorubicin in Nonfunctional Pituitary Adenoma Cells. Endocrinology, 2013; 154: 1414-1423;


9. Liu D, Wang S, Cui Y, Shen L, Du Y, Li G, Zhang B , Wang R. Sonic hedgehog elevates N- myc gene expression in neural stem cells. Neural Regen Res. 2012; 7(22):1703-1708.


10. Zhang B, Wang RZ, Lian ZG, Song Y, Yao Y. Neurogenesis by the activation of inherent neural stem cells in the rat hippocampus after cerebral infarction. Chin Med Sci J, 2009; 24(1):32-6.


11. Liu X, Ma S, Yao Y, Li G, Feng M, Deng K, Dai C, Cai F, Li Y, Zhang B, Wang R. Differential Expression of Folate Receptor Alpha in Pituitary Adenomas and Its Relationship to Tumor Behavior. Neurosurgery, 2012, 70:1274–1280.


12. Zhang B, Wang RZ, Lian ZG, Song Y, Yao Y. Experimental Study on Plasticity of Proliferated Neural Stem Cells in Adult Rats After Cerebral Infarction. Chin Med Sci J, 2006, 21(3):184-8.


13. Ma S, Liu X, Yao Y, Cai F, Dai C, Bao X, Feng M, Wei J, Zhang B, Li G, Ma W, Wang R. Effect of temozolomide on cell viability in gonadotroph adenoma cell lines. Oncology Reports 2011, 26: 543-50.


14. Zhang B, Wang RZ, Yao Y, Wang X, Li GL, Dou WC, Tian SQ, Zheng T, Tian Y. Experimental Study on the Proliferation and Differentiation of Neural Stem Cells in he Adult Rats after Cerebral Infarction. Natl Med J China, 2003, 83(22):1975-1979.


15. Zhang Bo, Wang Ren-zhi, Liu Jianyong, Lian Zhigang, Yao Yong, Wei Yukui, Li Shifang. ProliferationˈDifferentiation and Plasticity of Neural Stem Cells in the Adult Rats after Cerebral Infarction. Chin J Nerosurg, 2004, 20(5):400-404.


16. Zhang Bo, Wang Ren-zhi, Yao Yong. Activation of Endocrine Neural Stem Cells and Brain Ischemia. Chin J Nerosurg, 2003, 19(6):476-478.


17. Zhang Bo, Wang Ren-zhi, Zheng Tong. The Strategy and Approaches in Application of Celluar and Molecuar Neurosurgery. Mod J Neurol Neurosurg, 2003, 3(6)372-374.

Research Projects/Grants

1. National Natural Science Foundation: Deficiency in the oxidation pathway of DNA methylation promotes the invasive growth of pituitary adenomas. 2014-2017 the amount of patronage: 700,000 RMB

2. National Natural Science Foundation: Molecular imaging and in vivo tracking of Bmi1 transfected neural stem cells in brain. 2012.1-2012.12 the amount of patronage: 140,000RMB

3. Subtopic of national science and technology support program:  Pituitary adenoma individualized and comprehensive treatment based on molecular pathology. 2014-2017 the amount of patronage: 450,000 RMB

Admission Plan/Requirements

Admission Plan

PhD，1 person
Master，1 person